Author: Le-Viet, Nhiem; Le, Viet-Nho; Chung, Hai; Phan, Duc-Tuan; Phan, Quang-Duong; Cao, Thanh-Van; Abat, Cédric; Raoult, Didier; Parola, Philippe
Title: Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam Document date: 2019_3_4
ID: 0uwm4dk9_1
Snippet: Acute undifferentiated fever (AUF) is a temporary febrile illness accompanied by nonspecific manifestations [1] . It is frequently observed in clinical practice, but the diagnosis of its causes, particularly in developing and tropical countries, is often a challenge for clinicians due to the diversity of potential causes and the limited availability of diagnostic tools [1, 2] . In addition, the research on febrile illness has many gaps, such as t.....
Document: Acute undifferentiated fever (AUF) is a temporary febrile illness accompanied by nonspecific manifestations [1] . It is frequently observed in clinical practice, but the diagnosis of its causes, particularly in developing and tropical countries, is often a challenge for clinicians due to the diversity of potential causes and the limited availability of diagnostic tools [1, 2] . In addition, the research on febrile illness has many gaps, such as the limited epidemiological knowledge of fevers, the use of nonspecific tests and the lack of control groups, which limit the ability to definitively conclude the role of an infectious agent as the cause of AUF [1, 3] . Therefore, prospective studies enrolling patients with AUF and controls, using paired sera for serological tests as well as direct methods of pathogen detection, are necessary to better decipher the aetiologies of AUF. Accordingly, the results obtained from such studies can lead to recommendations regarding prophylactic and/or treatment measures for local populations and travellers.
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