Selected article for: "dengue infection and health problem"
Author: Le-Viet, Nhiem; Le, Viet-Nho; Chung, Hai; Phan, Duc-Tuan; Phan, Quang-Duong; Cao, Thanh-Van; Abat, Cédric; Raoult, Didier; Parola, Philippe
Title: Prospective case-control analysis of the aetiologies of acute undifferentiated fever in Vietnam
  • Document date: 2019_3_4
    • ID: 0uwm4dk9_35
    Snippet: Dengue infection remains a major health problem in Vietnam, where its incidence has increased over the past three decades (annual average percentage change from 1980 to 2010: 10.4%) [33] . Dengue cases occur throughout the year, but peaks are detected between June and October [34] . The dengue proportion of 11.1% detected in our study is underestimated because patients with dengue-positive RDTs were excluded from the study. The known sensitivity .....
    Document: Dengue infection remains a major health problem in Vietnam, where its incidence has increased over the past three decades (annual average percentage change from 1980 to 2010: 10.4%) [33] . Dengue cases occur throughout the year, but peaks are detected between June and October [34] . The dengue proportion of 11.1% detected in our study is underestimated because patients with dengue-positive RDTs were excluded from the study. The known sensitivity (6.4-81.5%) of the RDTs could lead to the misdiagnosis of dengue infection cases [35, 36] . A clinical analysis focusing on 28 patients with dengue monoinfection showed almost nonspecific manifestations, which were difficult to distinguish from other causes, even in two patients with petechiae (subcutaneous haemorrhages). Although thrombopenia and leukopoenia are not specific for dengue infection, these manifestations were observed more frequently in dengue cases than in the other cases included in our study.

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