Author: Moss, Ronald B
Title: Prospects for control of emerging infectious diseases with plasmid DNA vaccines Document date: 2009_9_7
ID: 1a5u7uux_34
Snippet: Additionally, a therapeutic DNA vaccine designed to treat dogs with skin cancer (melanoma) was granted conditional approval in 2007. This vaccine was developed through a collaboration of Memorial Sloan-Kettering Cancer Center (MSKCC) and Merial Ltd. Canine melanoma is an aggressive form of cancer. Dogs with melanomas that have gone beyond initial stages typically have a lifespan of one to five months with conventional therapies. In addition, the .....
Document: Additionally, a therapeutic DNA vaccine designed to treat dogs with skin cancer (melanoma) was granted conditional approval in 2007. This vaccine was developed through a collaboration of Memorial Sloan-Kettering Cancer Center (MSKCC) and Merial Ltd. Canine melanoma is an aggressive form of cancer. Dogs with melanomas that have gone beyond initial stages typically have a lifespan of one to five months with conventional therapies. In addition, the cancer is often resistant to chemotherapy. In a study of the DNA vaccine conducted by MSKCC, many dogs who received the vaccinations lived beyond the average 13 month survival [35] . Based on the significantly extended survival, the USDA gave this DNA vaccine conditional approval in 2007. This is the first therapeutic vaccine approved by the U.S. government for the treatment of cancer in animals or humans.
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