Author: Zhai, Shao-Lun; Lu, Shou-Sheng; Wei, Wen-Kang; Lv, Dian-Hong; Wen, Xiao-Hui; Zhai, Qi; Chen, Qin-Ling; Sun, Yan-Wei; Xi, Yun
Title: Reservoirs of Porcine Circoviruses: A Mini Review Document date: 2019_9_19
ID: 1e8qah7d_15
Snippet: There has always been controversy regarding PCVs infecting human. At the outset, Tischer et al. confirmed the presence of PCV1 antibodies in human sera, and the IFA results showed a significantly higher number of positive sera (20%) in non-hospitalized "healthy" persons from the former German Democratic Republic than that (8.6%) in blood donors from Berlin-West (14) . Interestingly, scientists from Northern Ireland, the United States, and Germany.....
Document: There has always been controversy regarding PCVs infecting human. At the outset, Tischer et al. confirmed the presence of PCV1 antibodies in human sera, and the IFA results showed a significantly higher number of positive sera (20%) in non-hospitalized "healthy" persons from the former German Democratic Republic than that (8.6%) in blood donors from Berlin-West (14) . Interestingly, scientists from Northern Ireland, the United States, and Germany could not detect antibodies or antigens of PCV2 in human samples (56) (57) (58) (59) . However, in other studies, antibody of PCV1 or antigen of PCV2 was detected in human sera, digestive tract samples and respiratory tract samples (60) (61) (62) (63) (64) (65) . Although there is serological and molecular proof of PCV presence in humans, the detection rate is very low. Thus, the clinical significance of PCVs in human beings remains largely unknown.
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