Author: Muñoz-González, Sara; Ruggli, Nicolas; Rosell, Rosa; Pérez, Lester Josué; Frías-Leuporeau, Maria Teresa; Fraile, Lorenzo; Montoya, Maria; Cordoba, Lorena; Domingo, Mariano; Ehrensperger, Felix; Summerfield, Artur; Ganges, Llilianne
Title: Postnatal Persistent Infection with Classical Swine Fever Virus and Its Immunological Implications Document date: 2015_5_4
ID: 13cii3on_45
Snippet: To the best of our knowledge, this is the first comprehensive study showing the ability of CSFV to generate viral persistence after early postnatal infection, which has not been described with other members of the Pestivirus genus either. In endemic areas where serological methods are used without virus detection in CSFV surveillance, postnatally persistently infected piglets would remain unnoticed. In addition to the epidemiological and economic.....
Document: To the best of our knowledge, this is the first comprehensive study showing the ability of CSFV to generate viral persistence after early postnatal infection, which has not been described with other members of the Pestivirus genus either. In endemic areas where serological methods are used without virus detection in CSFV surveillance, postnatally persistently infected piglets would remain unnoticed. In addition to the epidemiological and economic significance of persistent CSFV infections, this model will be useful for understanding the mechanisms of viral persistence.
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