Author: Pinheiro, Aruanã Joaquim Matheus Costa Rodrigues; Gonçalves, Jaciara Sá; Dourado, Ádylla Wilenna Alves; de Sousa, Eduardo Martins; Brito, Natilene Mesquita; Silva, Lanna Karinny; Batista, Marisa Cristina Aranha; de Sá, Joicy Cortez; Monteiro, Cinara Regina Aragão Vieira; Fernandes, Elizabeth Soares; Monteiro-Neto, Valério; Campbell, Lee Ann; Zago, Patrícia Maria Wiziack; Lima-Neto, Lidio Gonçalves
Title: Punica granatum L. Leaf Extract Attenuates Lung Inflammation in Mice with Acute Lung Injury Document date: 2018_2_20
ID: 0e9lq1b5_1
Snippet: Acute lung injury (ALI) is a clinical condition that causes disruption of the lung endothelial tissue and epithelial barrier and loss of lung function [1, 2] . ALI incidence remains high, and it is associated with high rates of mortality and morbidity worldwide, especially in developing countries [3] . ALI is characterized by intense transepithelial leukocyte infiltration, exudate accumulation in the lungs, loss of integrity of the alveolar-capil.....
Document: Acute lung injury (ALI) is a clinical condition that causes disruption of the lung endothelial tissue and epithelial barrier and loss of lung function [1, 2] . ALI incidence remains high, and it is associated with high rates of mortality and morbidity worldwide, especially in developing countries [3] . ALI is characterized by intense transepithelial leukocyte infiltration, exudate accumulation in the lungs, loss of integrity of the alveolar-capillary membrane, and tissue damage [4] . This response has been suggested to be due to the increased production of inflammatory mediators including cytokines (TNF-α, IL-1β, and IL-6), especially by alveolar macrophages and neutrophils [5] .
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