Author: Wang, Li; Xia, Tian; Guo, Tiantian; Ru, Yi; Jiang, Yanping; Cui, Wen; Zhou, Han; Qiao, Xinyuan; Tang, Lijie; Xu, Yigang; Li, Yijing
Title: Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits Document date: 2019_11_2
ID: 1apf9w7j_45
Snippet: To assess immunoprotective efficacy, the three groups of rabbits administered pPG-eGFP-VP60/LC393, inactivated vaccine, or PBS were infected with 1 mL RHDV (RNA copy number of 1.0 × 10 5.97 ) at 7 days after the last booster. Our results show that all rabbits in the PBS group died within three days post-challenge, while the rabbits immunized with recombinant L. casei or inactivated vaccine were completely protected against challenge with RHDV ( .....
Document: To assess immunoprotective efficacy, the three groups of rabbits administered pPG-eGFP-VP60/LC393, inactivated vaccine, or PBS were infected with 1 mL RHDV (RNA copy number of 1.0 × 10 5.97 ) at 7 days after the last booster. Our results show that all rabbits in the PBS group died within three days post-challenge, while the rabbits immunized with recombinant L. casei or inactivated vaccine were completely protected against challenge with RHDV ( Figure 7) .
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