Author: Atkins, John F.; Loughran, Gary; Bhatt, Pramod R.; Firth, Andrew E.; Baranov, Pavel V.
Title: Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use Document date: 2016_9_6
ID: 0s8huajd_202
Snippet: Once a ribosome has embarked on the frameshift pathway, the nucleotide composition of the shift region determines the outcome. One of these studies on dnaX frameshifting found supportive evidence for relevance of ribosomal P-site editing (392) . This study used bacterial strain MRE6000, which has an E. coli B-like release factor 2, i.e. 'WT' (M. O'Connor, personal communication; (582) ). P-site editing was initially reported (356, 583) in a strai.....
Document: Once a ribosome has embarked on the frameshift pathway, the nucleotide composition of the shift region determines the outcome. One of these studies on dnaX frameshifting found supportive evidence for relevance of ribosomal P-site editing (392) . This study used bacterial strain MRE6000, which has an E. coli B-like release factor 2, i.e. 'WT' (M. O'Connor, personal communication; (582) ). P-site editing was initially reported (356, 583) in a strain containing a partially defective release factor 2, which, on its own, would make general significance extrapolations problematic (584) .
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