Author: Kuban-Jankowska, Alicja; Sahu, Kamlesh K; Niedzialkowski, Pawel; Gorska, Magdalena; Tuszynski, Jack A; Ossowski, Tadeusz; Wozniak, Michal
Title: Redox process is crucial for inhibitory properties of aurintricarboxylic acid against activity of YopH: virulence factor of Yersinia pestis Document date: 2015_7_22
ID: 1irvzt8v_12
Snippet: YopH recombinant phosphatase from Yersinia pestis and Yersinia eneterocolitica was treated with ATA and IC 50 values were calculated. We also treated YopHs with peroctanoic acid, containing a peroxycarboxyl group with a higher oxidizing potency than that of a carboxyl group, studied by our group as a strong PTP inhibitor [20] , in order to compare the inhibitory effects. In addition, the human CD45 recombinant protein tyrosine phosphatase was uti.....
Document: YopH recombinant phosphatase from Yersinia pestis and Yersinia eneterocolitica was treated with ATA and IC 50 values were calculated. We also treated YopHs with peroctanoic acid, containing a peroxycarboxyl group with a higher oxidizing potency than that of a carboxyl group, studied by our group as a strong PTP inhibitor [20] , in order to compare the inhibitory effects. In addition, the human CD45 recombinant protein tyrosine phosphatase was utilized to study the inhibitory properties of ATA on human PTP.
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