Selected article for: "drug candidate and new treatment"
Author: Kuban-Jankowska, Alicja; Sahu, Kamlesh K; Niedzialkowski, Pawel; Gorska, Magdalena; Tuszynski, Jack A; Ossowski, Tadeusz; Wozniak, Michal
Title: Redox process is crucial for inhibitory properties of aurintricarboxylic acid against activity of YopH: virulence factor of Yersinia pestis
  • Document date: 2015_7_22
    • ID: 1irvzt8v_6
    Snippet: Yersinia pestis still causes several thousand human cases per year and the climate change is increasing the risk of plague outbreaks in new geographic areas as well as spreading of its natural reservoirs [10] . For historical reasons and due to the fact that Yersinia pestis is one of the most virulent infectious agents threatening humans, there is an ever increasing risk of the use of Y. pestis by unauthorized groups as a biological weapon of ter.....
    Document: Yersinia pestis still causes several thousand human cases per year and the climate change is increasing the risk of plague outbreaks in new geographic areas as well as spreading of its natural reservoirs [10] . For historical reasons and due to the fact that Yersinia pestis is one of the most virulent infectious agents threatening humans, there is an ever increasing risk of the use of Y. pestis by unauthorized groups as a biological weapon of terror [11] . The growing resistance of humans to antibiotics is one of the reasons to search for new treatment options and the bacterial virulence factor YopH is well positioned to become a new candidate for drug discovery [12] .

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