Author: Wang, Li; Xia, Tian; Guo, Tiantian; Ru, Yi; Jiang, Yanping; Cui, Wen; Zhou, Han; Qiao, Xinyuan; Tang, Lijie; Xu, Yigang; Li, Yijing
Title: Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits Document date: 2019_11_2
ID: 1apf9w7j_2
Snippet: Vaccination is the main approach for controlling RHDV because no effective treatment is available for this disease. Inactivated vaccines against RHDV were introduced in the early 1990s, improving the survival of rabbits on rabbit farms [7, 14] . However, RHDV inactivated vaccines are manufactured using the livers of rabbits infected with RHDV. This is because RHDV cannot grow in any continuous cell lines. Therefore, biological risks, animal-welfa.....
Document: Vaccination is the main approach for controlling RHDV because no effective treatment is available for this disease. Inactivated vaccines against RHDV were introduced in the early 1990s, improving the survival of rabbits on rabbit farms [7, 14] . However, RHDV inactivated vaccines are manufactured using the livers of rabbits infected with RHDV. This is because RHDV cannot grow in any continuous cell lines. Therefore, biological risks, animal-welfare concerns, and high costs are the major bottleneck problems in the production and usage of tissue-inactivated vaccines [2] .
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