Author: Atkins, John F.; Loughran, Gary; Bhatt, Pramod R.; Firth, Andrew E.; Baranov, Pavel V.
Title: Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use Document date: 2016_9_6
ID: 0s8huajd_144
Snippet: In certain circumstances herpes viruses avail of a parallel, and dramatic 100-fold, effect on frameshifting efficiency of not having a stop codon on the new frame (6) . In this case the spacing of ribosomes is relevant, though how is unknown. However, the issue is more general as the influence of ribosome spacing, mostly but not exclusively dictated by ribosome loading rate at initiation, on diverse instances of frameshifting is relatively under-.....
Document: In certain circumstances herpes viruses avail of a parallel, and dramatic 100-fold, effect on frameshifting efficiency of not having a stop codon on the new frame (6) . In this case the spacing of ribosomes is relevant, though how is unknown. However, the issue is more general as the influence of ribosome spacing, mostly but not exclusively dictated by ribosome loading rate at initiation, on diverse instances of frameshifting is relatively under-studied despite its likely relevance.
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