Selected article for: "cell line and overexpression cell line"

Author: Stepanov, Grigory A.; Filippova, Julia A.; Komissarov, Andrey B.; Kuligina, Elena V.; Richter, Vladimir A.; Semenov, Dmitry V.
Title: Regulatory Role of Small Nucleolar RNAs in Human Diseases
  • Document date: 2015_4_28
  • ID: 0ws5q37g_17
    Snippet: SnoRNA expression level was found decreased in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) cells, compared to normal cells [50] . Underexpression has been reported for another class of ncRNAs, microRNAs, in several types of cancers [50, 51] . However, a few snoRNAs are overexpressed in some AML cases. Specific overexpression has been reported for several orphan box C/D RNAs: SNORD112-114, encoded within the DLK1-Dio3 locus.....
    Document: SnoRNA expression level was found decreased in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) cells, compared to normal cells [50] . Underexpression has been reported for another class of ncRNAs, microRNAs, in several types of cancers [50, 51] . However, a few snoRNAs are overexpressed in some AML cases. Specific overexpression has been reported for several orphan box C/D RNAs: SNORD112-114, encoded within the DLK1-Dio3 locus of chromosome 14. SNORD114-1 has been shown to promote cell cycle progression through G0/G1 to S phase transition [50] . Overexpression of SNORD114-1 activates proliferation in K562 cell line, while targeted suppression of the box C/D RNA leads to the induction of cell death. The data implicate that some of these box C/D RNAs participate in the development of leukemia.

    Search related documents:
    Co phrase search for related documents
    • cell line and lymphoblastic leukemia: 1
    • cell line and myeloid leukemia: 1, 2, 3, 4, 5, 6, 7, 8
    • cell line and normal cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51
    • cell line and phase transition: 1, 2, 3
    • cell line and specific overexpression: 1, 2, 3, 4
    • expression level and lymphoblastic leukemia: 1
    • expression level and myeloid leukemia: 1
    • expression level and normal cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • expression level and phase transition: 1, 2
    • expression level and snorna expression level: 1, 2, 3, 4, 5
    • expression level and target suppression: 1
    • leukemia development and lymphoblastic leukemia: 1, 2, 3, 4
    • leukemia development and myeloid leukemia: 1, 2, 3, 4, 5
    • leukemia development and normal cell: 1
    • lymphoblastic leukemia and myeloid leukemia: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31
    • lymphoblastic leukemia and normal cell: 1
    • myeloid leukemia and normal cell: 1, 2, 3, 4, 5, 6
    • myeloid leukemia and phase transition: 1
    • normal cell and phase transition: 1