Author: Atkins, John F.; Loughran, Gary; Bhatt, Pramod R.; Firth, Andrew E.; Baranov, Pavel V.
Title: Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use Document date: 2016_9_6
ID: 0s8huajd_19
Snippet: A big majority of ribosomal frameshifting occurrences, especially −1, involve dissociation of P-site tRNA anticodon: codon pairing and realignment with re-pairing to mRNA at a new and overlapping codon. Frameshifting involving re-pairing at a non-overlapping new frame codon (hopping/bypassing), (54) (55) (56) appears much less frequent. When a 'stop hop' occurs with 9 nts encoding a single amino acid (54) , the distinction at the product level .....
Document: A big majority of ribosomal frameshifting occurrences, especially −1, involve dissociation of P-site tRNA anticodon: codon pairing and realignment with re-pairing to mRNA at a new and overlapping codon. Frameshifting involving re-pairing at a non-overlapping new frame codon (hopping/bypassing), (54) (55) (56) appears much less frequent. When a 'stop hop' occurs with 9 nts encoding a single amino acid (54) , the distinction at the product level from stop codon readthrough is two fewer amino acids.
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