Selected article for: "protein fold and RNA polymerase"
Author: Atkins, John F.; Loughran, Gary; Bhatt, Pramod R.; Firth, Andrew E.; Baranov, Pavel V.
Title: Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use
  • Document date: 2016_9_6
    • ID: 0s8huajd_34
    Snippet: Instead of frameshifting being relevant to downstream polymerase synthesis, some unclassified picorna-like viruses such as Acyrthosiphon pisum virus (116) , and Solenopsis invicta virus 3 (117) utilize frameshifting 3 of their polymerase encoding sequence. They have two long ORFs with their ORF1 encoding their RNA dependent RNA polymerase 5 of sequence encoding the capsid proteins. A −1 frameshift site at the end of the sequence for the 3 -enco.....
    Document: Instead of frameshifting being relevant to downstream polymerase synthesis, some unclassified picorna-like viruses such as Acyrthosiphon pisum virus (116) , and Solenopsis invicta virus 3 (117) utilize frameshifting 3 of their polymerase encoding sequence. They have two long ORFs with their ORF1 encoding their RNA dependent RNA polymerase 5 of sequence encoding the capsid proteins. A −1 frameshift site at the end of the sequence for the 3 -encoded, and jelly-roll fold containing, protein permits some ribosome to decode ORF2. This frameshifting results in a proportion of the jelly-roll fold protein having an extension that protrudes from the virion capsid, and also the synthesis of other proteins.

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