Author: Tchitchek, Nicolas; Eisfeld, Amie J; Tisoncik-Go, Jennifer; Josset, Laurence; Gralinski, Lisa E; Bécavin, Christophe; Tilton, Susan C; Webb-Robertson, Bobbie-Jo; Ferris, Martin T; Totura, Allison L; Li, Chengjun; Neumann, Gabriele; Metz, Thomas O; Smith, Richard D; Waters, Katrina M; Baric, Ralph; Kawaoka, Yoshihiro; Katze, Michael G
Title: Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice Document date: 2013_7_29
ID: 1qc72ovc_42
Snippet: The MDS Reference Maps and Projections representations that we developed and used in the context of this study were particularly useful to drive our analysis. By using the VN1203 wild-type virus -omics profiles as a reference representation, we have been able to observe the behavior of the host response to the other variants. Traditional visualization representation methods do not naturally allow fixed positions of a subset of highdimensional obj.....
Document: The MDS Reference Maps and Projections representations that we developed and used in the context of this study were particularly useful to drive our analysis. By using the VN1203 wild-type virus -omics profiles as a reference representation, we have been able to observe the behavior of the host response to the other variants. Traditional visualization representation methods do not naturally allow fixed positions of a subset of highdimensional objects. In the context of the development of novel visualization methods [40] [41] [42] , we showed the relevance of this approach for the analysis of large datasets.
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