Author: Liu, Weiwei; Ding, Chan
Title: Roles of LncRNAs in Viral Infections Document date: 2017_5_26
ID: 02zv1gsq_22
Snippet: Polyadenylated nuclear RNA (PAN) is encoded by Kaposi sarcoma-associated herpes virus (KSHV) and was first identified as a novel abundant 1.2-kb RNA that is transcribed by RNA Polymerase II (Sun et al., 1996) . PAN binds host poly (A)binding protein C1 (PABPC1) after PABPC1 is translocated to the nucleus during the lytic phase of infection and is required for the late KSHV gene expression, such as vIL-6 and k8.1 (Borah et al., 2011) . PAN also in.....
Document: Polyadenylated nuclear RNA (PAN) is encoded by Kaposi sarcoma-associated herpes virus (KSHV) and was first identified as a novel abundant 1.2-kb RNA that is transcribed by RNA Polymerase II (Sun et al., 1996) . PAN binds host poly (A)binding protein C1 (PABPC1) after PABPC1 is translocated to the nucleus during the lytic phase of infection and is required for the late KSHV gene expression, such as vIL-6 and k8.1 (Borah et al., 2011) . PAN also interacts with the ORF50 promoter and can either repress gene expression by interacting with protein components of polycomb repression complex 2 (PRC2) to mediate the trimethylation of H3K27 or activate gene expression by interacting with UTX, JMJD3 and the histone methyltransferase MLL2 to mediate the removal of the H3K27me3 mark and simultaneously mark it for activation (Rossetto and Pari, 2012; Rossetto et al., 2013 Rossetto et al., , 2016 .
Search related documents:
Co phrase search for related documents- gene expression activate and KSHV gene expression: 1
- gene expression activate and PABPC1 protein c1: 1
- gene expression activate and protein c1: 1
- gene expression and herpes virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- gene expression and KSHV gene expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- gene expression and lytic phase: 1, 2
- gene expression and nucleus translocate: 1
- gene expression and PABPC1 protein c1: 1
- gene expression and protein c1: 1, 2
- gene expression and protein component: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- gene expression repress and herpes virus: 1
- herpes virus and infection lytic phase: 1
- herpes virus and KSHV gene expression: 1
- herpes virus and lytic phase: 1
- infection lytic phase and lytic phase: 1, 2, 3, 4
- KSHV gene expression and PABPC1 protein c1: 1
- KSHV gene expression and protein c1: 1
- PABPC1 protein c1 and protein c1: 1
Co phrase search for related documents, hyperlinks ordered by date