Author: Liu, Weiwei; Ding, Chan
Title: Roles of LncRNAs in Viral Infections Document date: 2017_5_26
ID: 02zv1gsq_4
Snippet: LncRNAs regulate numerous cellular processes such as gene imprinting, regulation of the p53 pathway, stem cell self-renewal and differentiation, and DNA damage response (Latos et al., 2012; Liu et al., 2013; Yang et al., 2014; Sharma et al., 2015) . MiRNAs (about 19-25 nt in length) are known to take part in many of these cellular activities (Ameres and Zamore, 2013; Ha and Kim, 2014) . MiRNAs modulate mRNA degradation or translation by basepairi.....
Document: LncRNAs regulate numerous cellular processes such as gene imprinting, regulation of the p53 pathway, stem cell self-renewal and differentiation, and DNA damage response (Latos et al., 2012; Liu et al., 2013; Yang et al., 2014; Sharma et al., 2015) . MiRNAs (about 19-25 nt in length) are known to take part in many of these cellular activities (Ameres and Zamore, 2013; Ha and Kim, 2014) . MiRNAs modulate mRNA degradation or translation by basepairing to sequence motifs of mRNAs. In contrast, lncRNAs utilize a multitude of mechanisms, mediated by their specific sequences or structural motifs that bind DNA, RNA, or protein.
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