Author: Abdel-Moneim, Ahmed S; El-Kady, Magdy F; Ladman, Brian S; Gelb, Jack
Title: S1 gene sequence analysis of a nephropathogenic strain of avian infectious bronchitis virus in Egypt Document date: 2006_9_20
ID: 1in7m56w_2
Snippet: Variation in S1 sequences [9] [10] [11] , has been recently used for distinguishing between different IBV serotypes. Diversity in S1 probably results from mutation, recombination and strong positive selection in vivo [12] . Antigenically different serotypes and newly emerged variants from field chicken flocks sometimes cause vaccine breaks. The generation of genetic variants is thought to be resulted from few amino acid changes in the spike (S) g.....
Document: Variation in S1 sequences [9] [10] [11] , has been recently used for distinguishing between different IBV serotypes. Diversity in S1 probably results from mutation, recombination and strong positive selection in vivo [12] . Antigenically different serotypes and newly emerged variants from field chicken flocks sometimes cause vaccine breaks. The generation of genetic variants is thought to be resulted from few amino acid changes in the spike (S) glycoprotein of IBV [13, 14] .
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