Author: Frieman, Matthew B.; Chen, Jun; Morrison, Thomas E.; Whitmore, Alan; Funkhouser, William; Ward, Jerrold M.; Lamirande, Elaine W.; Roberts, Anjeanette; Heise, Mark; Subbarao, Kanta; Baric, Ralph S.
Title: SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism Document date: 2010_4_8
ID: 15rtwl26_51
Snippet: All mice in this study were treated following IACUC guidelines. For infection mice were pre-treated with Ketamine and Xylazine as an anesthetic. Mice were euthanized if their weight dropped below 20% of their starting weight or if clinical symptoms warranted it per our IACUC approvals. Animal housing and care and experimental protocols were in accordance with all UNC-Chapel Hill Institutional Animal Care and Use Committee guidelines or NIH guidel.....
Document: All mice in this study were treated following IACUC guidelines. For infection mice were pre-treated with Ketamine and Xylazine as an anesthetic. Mice were euthanized if their weight dropped below 20% of their starting weight or if clinical symptoms warranted it per our IACUC approvals. Animal housing and care and experimental protocols were in accordance with all UNC-Chapel Hill Institutional Animal Care and Use Committee guidelines or NIH guidelines, depending where the experiments were performed.
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