Selected article for: "digoxin ouabain and JEV infection"

Author: Guo, Jiao; Jia, Xiaoying; Liu, Yang; Wang, Shaobo; Cao, Junyuan; Zhang, Bo; Xiao, Gengfu; Wang, Wei
Title: Screening of Natural Extracts for Inhibitors against Japanese Encephalitis Virus Infection
  • Document date: 2020_2_21
  • ID: 161ck1i9_8
    Snippet: To confirm this hypothesis, Huh-7 cells electroporated with the JEV replicon were treated with the indicated concentration of ouabain and digoxin; we revealed the Our results indicated that both drugs inhibited JEV RNA synthesis in a dose-dependent manner, while neither drug inhibited the initial translation of replicon RNA, confirming that these drugs inhibit JEV infection at the replication stage......
    Document: To confirm this hypothesis, Huh-7 cells electroporated with the JEV replicon were treated with the indicated concentration of ouabain and digoxin; we revealed the Our results indicated that both drugs inhibited JEV RNA synthesis in a dose-dependent manner, while neither drug inhibited the initial translation of replicon RNA, confirming that these drugs inhibit JEV infection at the replication stage.

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