Selected article for: "International license and pandemic outbreak"
Author: Natalia Fintelman-Rodrigues; Carolina Q. Sacramento; Carlyle Ribeiro Lima; Franklin Souza da Silva; André C. Ferreira; Mayara Mattos; Caroline S. de Freitas; Vinicius Cardoso Soares; Suelen da Silva Gomes Dias; Jairo R. Temerozo; Milene Miranda; Aline R. Matos; Fernando A. Bozza; Nicolas Carels; Carlos Roberto Alves; Marilda M. Siqueira; Patrícia T. Bozza; Thiago Moreno L. Souza
Title: Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production
  • Document date: 2020_4_5
    • ID: 6zk0ioep_5
    Snippet: Repurposing of clinically approved drugs is the fastest pathway towards an effective response to a pandemic outbreak 8 9 . This mega trial has been . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.04.020925 doi: bioRxiv preprint 4 putting forward lopinavir (LPV)/ritonavir (RTV), in combination or not wit.....
    Document: Repurposing of clinically approved drugs is the fastest pathway towards an effective response to a pandemic outbreak 8 9 . This mega trial has been . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.04.020925 doi: bioRxiv preprint 4 putting forward lopinavir (LPV)/ritonavir (RTV), in combination or not with interferonβ (IFN-β), chloroquine (CQ) and remdesivir to treat COVID-19 9 . LPV, RTV and remdesivir target viral enzymes, while the actions of CQ and IFN-β target host cells.

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