Author: Kun Sun; Liuqi Gu; Li Ma; Yunfeng Duan
Title: Atlas of ACE2 gene expression in mammals reveals novel insights in transmission of SARS-Cov-2 Document date: 2020_3_31
ID: 89sg0cpk_8
Snippet: Since SARS-CoV-2 invade both bat and human cells via ACE2, we reasoned that if animals have ACE2 proteins similar to human, they could also become the targets of SARS-CoV-2, we thus evaluated the conservation of ACE2 gene across mammals. We further investigated ACE2 expression in various tissues among human and common mammals. In particular, we included species that live in close proximity with humans, i.e., pets and livestock. Our analyses ident.....
Document: Since SARS-CoV-2 invade both bat and human cells via ACE2, we reasoned that if animals have ACE2 proteins similar to human, they could also become the targets of SARS-CoV-2, we thus evaluated the conservation of ACE2 gene across mammals. We further investigated ACE2 expression in various tissues among human and common mammals. In particular, we included species that live in close proximity with humans, i.e., pets and livestock. Our analyses identified potential species susceptible to SARS-. CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.30.015644 doi: bioRxiv preprint CoV-2 and yielded novel insights into virus tracing and transmission, which may further contribute to the prevention and control of the COVID-19 pandemic.
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