Selected article for: "crystal packing and mutant dimer"

Author: Xu, Xiaoling; Lou, Zhiyong; Ma, Yanlin; Chen, Xuehui; Yang, Zhangsheng; Tong, Xiaohang; Zhao, Qi; Xu, Yuanyuan; Deng, Hongyu; Bartlam, Mark; Rao, Zihe
Title: Crystal Structure of the C-Terminal Cytoplasmic Domain of Non-Structural Protein 4 from Mouse Hepatitis Virus A59
  • Document date: 2009_7_10
  • ID: 1beonuh7_23
    Snippet: The C425S mutant dimer was obtained by mutagenesis and crystal packing, and is unlikely to represent a physiological state. No enzymatic activity or biochemical studies have been reported for nsp4 to date, so further studies are required to confirm whether or not the WT nsp4C dimer is physiological......
    Document: The C425S mutant dimer was obtained by mutagenesis and crystal packing, and is unlikely to represent a physiological state. No enzymatic activity or biochemical studies have been reported for nsp4 to date, so further studies are required to confirm whether or not the WT nsp4C dimer is physiological.

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