Author: ten Oever, Jaap; Kox, Matthijs; van de Veerdonk, Frank L; Mothapo, Khutso M; Slavcovici, Adriana; Jansen, Tim L; Tweehuysen, Lieke; Giamarellos-Bourboulis, Evangelos J; Schneeberger, Peter M; Wever, Peter C; Stoffels, Monique; Simon, Anna; van der Meer, Jos WM; Johnson, Melissa D; Kullberg, Bart-Jan; Pickkers, Peter; Pachot, Alexandre; Joosten, Leo AB; Netea, Mihai G
Title: The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases Document date: 2014_11_19
ID: 0zkeoa1z_18
Snippet: In-vitro release of soluble TLRs by human PBMCs sTLR2 and sTLR4 were below the detection limit (6 and 8 ng/ml, respectively) in the supernatants of unstimulated PBMCs. After stimulation with LPS, Pam3Cys or heat-killed E. coli, significant amounts of IL-6, sTLR2 and sTLR4 were released by PBMCs in the supernatant, although shedding of sTLRs was not confined to stimulation of its corresponding cell surface receptor (Figure 1 )......
Document: In-vitro release of soluble TLRs by human PBMCs sTLR2 and sTLR4 were below the detection limit (6 and 8 ng/ml, respectively) in the supernatants of unstimulated PBMCs. After stimulation with LPS, Pam3Cys or heat-killed E. coli, significant amounts of IL-6, sTLR2 and sTLR4 were released by PBMCs in the supernatant, although shedding of sTLRs was not confined to stimulation of its corresponding cell surface receptor (Figure 1 ).
Search related documents:
Co phrase search for related documents- cell surface and human pbmc: 1, 2, 3
- cell surface and significant amount: 1, 2
- cell surface and vitro release: 1, 2, 3
- pbmc release and unstimulated pbmc: 1
Co phrase search for related documents, hyperlinks ordered by date