Author: Myllykoski, Matti; Kursula, Petri
Title: Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase Document date: 2017_1_31
ID: 0a3okta0_6
Snippet: The structure of the putative tRNA ligase LigT from E. coli was determined by X-ray crystallography in the apo form. In addition, a number of LigT complex structures with active-site ligands were solved, hence significantly extending the earlier results on the LigT structure, which was only available as a complex with the reaction product 2 0 -AMP [22] . Intriguingly, a total of five different crystal forms were observed in this study, which also.....
Document: The structure of the putative tRNA ligase LigT from E. coli was determined by X-ray crystallography in the apo form. In addition, a number of LigT complex structures with active-site ligands were solved, hence significantly extending the earlier results on the LigT structure, which was only available as a complex with the reaction product 2 0 -AMP [22] . Intriguingly, a total of five different crystal forms were observed in this study, which also highlights the flexible properties of the enzyme.
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