Author: Qiu, Yingshan; Lam, Jenny K. W.; Leung, Susan W. S.; Liang, Wanling
Title: Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside Document date: 2016_9_20
ID: 04pp3lv0_38
Snippet: RSV infection is one of the most common infections in children [2, 135] . In adult, RSV infection usually leads to self-limited upper respiratory illness [136] . However, severe RSV infection has been observed in elderly patients with lung diseases or in immunocompromised patients [137] . Current management of RSV includes bronchodilators, corticosteroids, antibiotics and supportive care [2] , but their efficacy is not satisfactory. To date, ther.....
Document: RSV infection is one of the most common infections in children [2, 135] . In adult, RSV infection usually leads to self-limited upper respiratory illness [136] . However, severe RSV infection has been observed in elderly patients with lung diseases or in immunocompromised patients [137] . Current management of RSV includes bronchodilators, corticosteroids, antibiotics and supportive care [2] , but their efficacy is not satisfactory. To date, there is no licensed vaccine available to prevent this disease [138] . There is an unmet need to develop effective RSV therapeutics and vaccines in both the pediatric and adult population.
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