Author: Brandon Malone; Boris Simovski; Clement Moline; Jun Cheng; Marius Gheorghe; Hugues Fontenelle; Ioannis Vardaxis; Simen Tennoe; Jenny-Ann Malmberg; Richard Stratford; Trevor Clancy
Title: Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2: toward universal blueprints for vaccine designs Document date: 2020_4_21
ID: cm30gyd8_19
Snippet: Epitope maps were created for all of the viral proteins and an example based on the IP scores for the S-protein is depicted in Figure 1A and for AP in Figure 1B , and illustrates distinct regions of the S-protein that contain candidate CD8 and CD4 epitopes for the 100 most frequent human HLA-A, HLA-B and HLA-DR alleles. Interestingly, the predicted B cell epitopes often map to regions of the protein that contain a high density of predicted T cell.....
Document: Epitope maps were created for all of the viral proteins and an example based on the IP scores for the S-protein is depicted in Figure 1A and for AP in Figure 1B , and illustrates distinct regions of the S-protein that contain candidate CD8 and CD4 epitopes for the 100 most frequent human HLA-A, HLA-B and HLA-DR alleles. Interestingly, the predicted B cell epitopes often map to regions of the protein that contain a high density of predicted T cell epitopes, thus the heat author/funder. All rights reserved. No reuse allowed without permission.
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