Author: Brandon Malone; Boris Simovski; Clement Moline; Jun Cheng; Marius Gheorghe; Hugues Fontenelle; Ioannis Vardaxis; Simen Tennoe; Jenny-Ann Malmberg; Richard Stratford; Trevor Clancy
Title: Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2: toward universal blueprints for vaccine designs Document date: 2020_4_21
ID: cm30gyd8_6
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.21.052084 doi: bioRxiv preprint facilitates viral entry into host cells [13] . Considering the potential for ADE, the reported short-lived antibody response [9, 10, 14] , and the documented pathological consequence of S-protein specific antibodies in certain animal models, it is worth considering alternative strategies for vaccine develop.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.21.052084 doi: bioRxiv preprint facilitates viral entry into host cells [13] . Considering the potential for ADE, the reported short-lived antibody response [9, 10, 14] , and the documented pathological consequence of S-protein specific antibodies in certain animal models, it is worth considering alternative strategies for vaccine development that drive T-cell responses from targets other than the S-protein when designing vaccines to combat coronaviridae infections.
Search related documents:
Co phrase search for related documents- alternative strategy and antibody response: 1, 2, 3
- alternative strategy and host cell: 1, 2, 3, 4, 5, 6, 7, 8, 9
- alternative strategy and specific antibody: 1, 2
- alternative strategy and vaccine design: 1, 2, 3, 4, 5
- animal model and antibody response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- animal model and host cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- animal model and specific antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
- animal model and vaccine design: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- antibody response and host cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- antibody response and pathological consequence: 1
- antibody response and specific antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- antibody response and vaccine design: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- coronaviridae infection and host cell: 1
- coronaviridae infection and vaccine design: 1
- host cell and specific antibody: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- host cell and vaccine design: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- pathological consequence and specific antibody: 1
- specific antibody and vaccine design: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date