Author: El-Faham, Ayman; Farooq, Muhammad; Khattab, Sherine N.; Abutaha, Nael; Wadaan, Mohammad A.; Ghabbour, Hazem A.; Fun, Hoong-Kun
Title: Synthesis, Characterization, and Anti-Cancer Activity of Some New N'-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives Document date: 2015_8_13
ID: 0dddrh4e_2
Snippet: Because of the remarkable biological value of isatin as an important constituent of bioactive compounds exhibiting caspase inhibitory [28, 29] , antibacterial, and antiproliferative activity [30] , Schiff bases of isatin derivatives have antismallpox [31] and GAL3 receptor antagonist capabilities [32] . In addition, the analogous of isatin derivatives displayed inhibitory activity against eLF2 kinase activator [33] , TNF-α, CDK2 [34] and SARS pr.....
Document: Because of the remarkable biological value of isatin as an important constituent of bioactive compounds exhibiting caspase inhibitory [28, 29] , antibacterial, and antiproliferative activity [30] , Schiff bases of isatin derivatives have antismallpox [31] and GAL3 receptor antagonist capabilities [32] . In addition, the analogous of isatin derivatives displayed inhibitory activity against eLF2 kinase activator [33] , TNF-α, CDK2 [34] and SARS protease [35] . Isatin also displays antiviral [36] , anti-inflammatory, analgesic [37] , and anticonvulsant activities [38] .
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