Author: ten Oever, Jaap; Kox, Matthijs; van de Veerdonk, Frank L; Mothapo, Khutso M; Slavcovici, Adriana; Jansen, Tim L; Tweehuysen, Lieke; Giamarellos-Bourboulis, Evangelos J; Schneeberger, Peter M; Wever, Peter C; Stoffels, Monique; Simon, Anna; van der Meer, Jos WM; Johnson, Melissa D; Kullberg, Bart-Jan; Pickkers, Peter; Pachot, Alexandre; Joosten, Leo AB; Netea, Mihai G
Title: The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases Document date: 2014_11_19
ID: 0zkeoa1z_16
Snippet: Receiver operating characteristics (ROC) curve statistics were applied to calculate sensitivity and specificity. In order to determine the diagnostic accuracy of the combination of biomarkers, logistic regression analysis was used to estimate the predicted probabilities, which were subsequently used for the generation of a ROC curve. The method described by DeLong was used for comparing areas under ROC curves (AUC) [22] . All tests were two-sided.....
Document: Receiver operating characteristics (ROC) curve statistics were applied to calculate sensitivity and specificity. In order to determine the diagnostic accuracy of the combination of biomarkers, logistic regression analysis was used to estimate the predicted probabilities, which were subsequently used for the generation of a ROC curve. The method described by DeLong was used for comparing areas under ROC curves (AUC) [22] . All tests were two-sided, and P < 0.05 was considered statistically significant. Data were analyzed using Graph Pad Prism 5 (GraphPad Software, La Jolla, CA) and MedCalc version 11.3.1.0 (MedCalc Software, Mariakerke, Belgium).
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