Author: Lien, Gi-Shih; Liu, Jen-Fang; Chien, Ming-Hsien; Hsu, Wei-Tse; Chang, Tzu-Hao; Ku, Chia-Chi; Ji, Andrea Tung-Qian; Tan, Peng; Hsieh, Ting-Lieh; Lee, Liang-Ming; Ho, Jennifer H
Title: The ability to suppress macrophage-mediated inflammation in orbital fat stem cells is controlled by miR-671-5p Document date: 2014_8_13
ID: 1i6hni9s_49
Snippet: OFSCs inhibit macrophage-mediated inflammation and induce macrophage cell cycle arrest by the paracrine effect. The activated macrophages trigger immunomodulating factor expressions in OFSCs such as IDO, IL-10, IL-1RA and sTNFR type II. Upregulation of IL-1RA and sTNFR type II in OFSCs in a cytokine-inducible fashion is initiated by degradation of miR-671-5p......
Document: OFSCs inhibit macrophage-mediated inflammation and induce macrophage cell cycle arrest by the paracrine effect. The activated macrophages trigger immunomodulating factor expressions in OFSCs such as IDO, IL-10, IL-1RA and sTNFR type II. Upregulation of IL-1RA and sTNFR type II in OFSCs in a cytokine-inducible fashion is initiated by degradation of miR-671-5p.
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