Author: Hoffmann, Markus; Krüger, Nadine; Zmora, Pawel; Wrensch, Florian; Herrler, Georg; Pöhlmann, Stefan
Title: The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells Document date: 2016_3_30
ID: 0ejhd9nw_1
Snippet: Influenza A viruses (FLUAV) are enveloped, negative stranded RNA viruses that pose a major threat to public health [1] . The ability of FLUAV to constantly adapt to immune pressure allows these viruses to continuously circulate in the human population, resulting in annual influenza epidemics (seasonal influenza [2, 3] ). Infants, children and the elderly are at particular risk of developing severe disease upon infection with seasonal FLUAV and it.....
Document: Influenza A viruses (FLUAV) are enveloped, negative stranded RNA viruses that pose a major threat to public health [1] . The ability of FLUAV to constantly adapt to immune pressure allows these viruses to continuously circulate in the human population, resulting in annual influenza epidemics (seasonal influenza [2, 3] ). Infants, children and the elderly are at particular risk of developing severe disease upon infection with seasonal FLUAV and it has been estimated that world-wide 250,000 to 500,000 people die each year of seasonal influenza [1] .
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