Author: Zapata, Juan Carlos; Carrion, Ricardo; Patterson, Jean L.; Crasta, Oswald; Zhang, Yan; Mani, Sachin; Jett, Marti; Poonia, Bhawna; Djavani, Mahmoud; White, David M.; Lukashevich, Igor S.; Salvato, Maria S.
Title: Transcriptome Analysis of Human Peripheral Blood Mononuclear Cells Exposed to Lassa Virus and to the Attenuated Mopeia/Lassa Reassortant 29 (ML29), a Vaccine Candidate Document date: 2013_9_12
ID: 0epeljaf_35
Snippet: LASV exposure up-regulates genes involved in innate immunity: IFN-stimulated genes, transcription factors, and genes involved in apoptosis As shown in Figure 2A , the most striking differences involved gene expression in three different functional categories: IFNstimulated, apoptosis, and NF-kB pathways, during the late timepoint, 24 h after exposure......
Document: LASV exposure up-regulates genes involved in innate immunity: IFN-stimulated genes, transcription factors, and genes involved in apoptosis As shown in Figure 2A , the most striking differences involved gene expression in three different functional categories: IFNstimulated, apoptosis, and NF-kB pathways, during the late timepoint, 24 h after exposure.
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