Synthesis, Characterization, Crystal Structure and Antimicrobial Activity of Copper(II) Complexes with the Schiff Base Derived from 2-Hydroxy-4-Methoxybenzaldehyde

Pahon?u, Elena; Ilie?, Diana-Carolina; Shova, Sergiu; Paraschivescu, Codru?a; Badea, Mihaela; Gulea, Aurelian; Ro?u, Tudor

Data from Table 5 confirm the fact that both the ligand HL and the coordinative complexes of copper have a reduced bacteriostatic activity within the limits of concentrations 0.5-10.0 mg/mL toward the gram-positive and gram-negative bacteria. A more nuanced sensitivity toward the searched complexes has been proved by the gram-positive micro-organisms. The experimental data obtained demonstrate that the bacteriostatic activity of the coordinative complexes is influenced by the number of ligand molecules HL found out in the inner sphere and ligand nature. Therefore, growing of the number of ligand molecules and replacing the ions chloro-or acetate-with the perchlorate ion leads to a growing of the antimicrobial activity.