Author: Hoffmann, Markus; González Hernández, Mariana; Berger, Elisabeth; Marzi, Andrea; Pöhlmann, Stefan
Title: The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent Document date: 2016_2_22
ID: 146cwh6y_35
Snippet: Comparative Analysis of Filovirus Entry into Human, Non-Human Primate and Bat Cell Lines protease inhibitors would reveal subtle differences in protease choice of EBOV in human and bat cells. Finally, there were no obvious differences between bat cells that either showed a comparable (EpoNi/22.1) or differential (EidNi/41) susceptibility for transduction by the seven GPs. These observations suggest that all filovirus GPs depend on the same host c.....
Document: Comparative Analysis of Filovirus Entry into Human, Non-Human Primate and Bat Cell Lines protease inhibitors would reveal subtle differences in protease choice of EBOV in human and bat cells. Finally, there were no obvious differences between bat cells that either showed a comparable (EpoNi/22.1) or differential (EidNi/41) susceptibility for transduction by the seven GPs. These observations suggest that all filovirus GPs depend on the same host cell factors for entry into human and fruit bat cell lines.
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