Selected article for: "bacterial infection and infectious cause"
Author: van Rijn, Anneloes L.; van Boheemen, Sander; Sidorov, Igor; Carbo, Ellen C.; Pappas, Nikos; Mei, Hailiang; Feltkamp, Mariet; Aanerud, Marianne; Bakke, Per; Claas, Eric C. J.; Eagan, Tomas M.; Hiemstra, Pieter S.; Kroes, Aloys C. M.; de Vries, Jutte J. C.
Title: The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
  • Document date: 2019_10_24
    • ID: 0rupk21u_59
    Snippet: The mNGS protocol used was highly sensitive and specific for semi-quantitative detection of respiratory pathogenic viruses. Excellent negative predictive value implicates the potential of mNGS to exclude a known viral infectious cause in one test, with consequences for clinical decision making. Reduced abundance of bacteriophages in COPD patients with viral pathogens implicates skewing of the virome, and speculatively the bacterial population, du.....
    Document: The mNGS protocol used was highly sensitive and specific for semi-quantitative detection of respiratory pathogenic viruses. Excellent negative predictive value implicates the potential of mNGS to exclude a known viral infectious cause in one test, with consequences for clinical decision making. Reduced abundance of bacteriophages in COPD patients with viral pathogens implicates skewing of the virome, and speculatively the bacterial population, during infection.

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