Author: David, Paul; Megger, Dominik A.; Kaiser, Tamara; Werner, Tanja; Liu, Jia; Chen, Lieping; Sitek, Barbara; Dittmer, Ulf; Zelinskyy, Gennadiy
Title: The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8(+) T Cells During an Acute Retroviral Infection Document date: 2019_2_5
ID: 0ael8imp_36
Snippet: production of Gzms showed a clear influence of the pathway on Gzm expression during the acute phase of antiviral T cell responses. During the early expansion of T cells and control of FV infection the PD-1 signaling pathway suppressed the simultaneous production of different Gzms in effector CD8 + cells......
Document: production of Gzms showed a clear influence of the pathway on Gzm expression during the acute phase of antiviral T cell responses. During the early expansion of T cells and control of FV infection the PD-1 signaling pathway suppressed the simultaneous production of different Gzms in effector CD8 + cells.
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