Author: van Rijn, Anneloes L.; van Boheemen, Sander; Sidorov, Igor; Carbo, Ellen C.; Pappas, Nikos; Mei, Hailiang; Feltkamp, Mariet; Aanerud, Marianne; Bakke, Per; Claas, Eric C. J.; Eagan, Tomas M.; Hiemstra, Pieter S.; Kroes, Aloys C. M.; de Vries, Jutte J. C.
Title: The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease Document date: 2019_10_24
ID: 0rupk21u_55
Snippet: The most abundant bacterial phyla detected in this study were comparable with other reports. Although the percentage of proteobacteria was relatively high when compared to other studies of the nasopharyngeal microbiome, our swabs are sampled during COPD exacerbations [44, 45] . Study of the lower airways by means of e.g. protected brushes during bronchoscopy is needed for further analysis of bacterial and viral (sub)populations including comparis.....
Document: The most abundant bacterial phyla detected in this study were comparable with other reports. Although the percentage of proteobacteria was relatively high when compared to other studies of the nasopharyngeal microbiome, our swabs are sampled during COPD exacerbations [44, 45] . Study of the lower airways by means of e.g. protected brushes during bronchoscopy is needed for further analysis of bacterial and viral (sub)populations including comparison with PCR and culture results. Studies comparing the respiratory virome during stable disease and exacerbations are needed to determine a potential correlation between the virome/bacteriome during stable state and disease progression or exacerbation frequency.
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