Author: Neufeldt, Christopher J.; Joyce, Michael A.; Van Buuren, Nicholas; Levin, Aviad; Kirkegaard, Karla; Gale Jr., Michael; Tyrrell, D. Lorne J.; Wozniak, Richard W.
Title: The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites Document date: 2016_2_10
ID: 1kuggdzj_18
Snippet: (NS5B and viral RNA) and the MAM membrane fraction enriched for viral assembly complexes (Core, NS3, and infections virus). Moreover, the lower percentage of viral RNA (~10% of total RNA) found in the MAM fraction with viral assembly components implies that the majority of the membrane-associated viral RNA within the cell is likely engaged in replication or translation rather than virion assembly......
Document: (NS5B and viral RNA) and the MAM membrane fraction enriched for viral assembly complexes (Core, NS3, and infections virus). Moreover, the lower percentage of viral RNA (~10% of total RNA) found in the MAM fraction with viral assembly components implies that the majority of the membrane-associated viral RNA within the cell is likely engaged in replication or translation rather than virion assembly.
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