Selected article for: "gene expression and post infection"
Author: Law, Helen KW; Cheung, Chung Yan; Sia, Sin Fun; Chan, Yuk On; Peiris, JS Malik; Lau, Yu Lung
Title: Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells
  • Document date: 2009_6_8
    • ID: 19noki6p_9
    Snippet: Gene expression of extracellular TLRs (TLR-1, TLR-2, TLR-4, TLR-5, TLR-6) in DCs are summarised in Fig. 1 . There was a low (<50 copies/per 10 4 β-actin), but significant upregulation of TLR-1 and TLR-2 in SARS-CoV infected adult DCs at 3 h post infection. A similar trend was observed in CB DCs but the difference did not reach statistical significance. In CB DCs, the basal gene expressions of TLR-1, TLR-2, and TLR-5 and the SARS-CoV induced TLR-.....
    Document: Gene expression of extracellular TLRs (TLR-1, TLR-2, TLR-4, TLR-5, TLR-6) in DCs are summarised in Fig. 1 . There was a low (<50 copies/per 10 4 β-actin), but significant upregulation of TLR-1 and TLR-2 in SARS-CoV infected adult DCs at 3 h post infection. A similar trend was observed in CB DCs but the difference did not reach statistical significance. In CB DCs, the basal gene expressions of TLR-1, TLR-2, and TLR-5 and the SARS-CoV induced TLR-2 and TLR-4 expression were significantly higher than that in adult DCs (Table 1) . No expression of TLR-10 was detected in either adult or CB DCs (data not shown).

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