Selected article for: "clinical sample and diagnostic value"
Author: van Rijn, Anneloes L.; van Boheemen, Sander; Sidorov, Igor; Carbo, Ellen C.; Pappas, Nikos; Mei, Hailiang; Feltkamp, Mariet; Aanerud, Marianne; Bakke, Per; Claas, Eric C. J.; Eagan, Tomas M.; Hiemstra, Pieter S.; Kroes, Aloys C. M.; de Vries, Jutte J. C.
Title: The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
  • Document date: 2019_10_24
    • ID: 0rupk21u_5
    Snippet: Metagenomic next generation sequencing (mNGS) is an innovative method, which enables the detection of all genomes in a given sample. Proof of principle studies have shown that mNGS on respiratory samples can confirm and extend PCR results and deliver typing and resistance data at the same time [10] [11] [12] [13] [14] . The performance of mNGS in the clinical diagnostic setting, especially the positive and negative predictive value, has not yet b.....
    Document: Metagenomic next generation sequencing (mNGS) is an innovative method, which enables the detection of all genomes in a given sample. Proof of principle studies have shown that mNGS on respiratory samples can confirm and extend PCR results and deliver typing and resistance data at the same time [10] [11] [12] [13] [14] . The performance of mNGS in the clinical diagnostic setting, especially the positive and negative predictive value, has not yet been elucidated and is likely to differ per clinical syndrome and sample.

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