Author: Romagosa, Anna; Allerson, Matt; Gramer, Marie; Joo, Han Soo; Deen, John; Detmer, Susan; Torremorell, Montserrat
Title: Vaccination of influenza a virus decreases transmission rates in pigs Document date: 2011_12_20
ID: 0q8fedqf_10
Snippet: Twenty-four hours post arrival all pigs were vaccinated according to their treatment group. Pigs in the HE group received 2 mL intramuscularly (IM) of a commercial licensed influenza vaccine (FluSure XP ® , Pfizer Animal Health, New York, USA). Pigs in the HO group were similarly vaccinated with a homologous, inactivated vaccine containing the same viral isolate as the challenge virus. Each vaccination was repeated two weeks later. The pigs in t.....
Document: Twenty-four hours post arrival all pigs were vaccinated according to their treatment group. Pigs in the HE group received 2 mL intramuscularly (IM) of a commercial licensed influenza vaccine (FluSure XP ® , Pfizer Animal Health, New York, USA). Pigs in the HO group were similarly vaccinated with a homologous, inactivated vaccine containing the same viral isolate as the challenge virus. Each vaccination was repeated two weeks later. The pigs in the NV group were injected with 2 mL of sterile saline solution IM in the neck at 2 weeks interval. In each room 1 of the 11 pigs (designated "seeder") was left unvaccinated to be intratracheally and intranasally challenged with influenza and serve as a source of infection for the other pigs in the group.
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