Author: Xudan Chen; Yang Zhang; Baoyi Zhu; Jianwen Zeng; Wenxin Hong; Xi He; Jingfeng Chen; Haipeng Zheng; Shuang Qiu; Ying Deng; Juliana Chan; Jian Wang
Title: Associations of clinical characteristics and antiviral drugs with viral RNA clearance in patients with COVID-19 in Guangzhou, China: a retrospective cohort study Document date: 2020_4_14
ID: 9j4ese89_39
Snippet: In conclusion, in patients with COVID-19, a minimum of 21 days' isolation since illness onset may be warranted even for asymptomatic patients. Old people are more likely to have serious illness with delayed clearance of viral RNA, and may require prolonged period of support and isolation. The use of antiviral drugs (chloroquine, oseltamivir, arbidol, and lopinavir/ritonavir) did not improve viral RNA clearance, while corticosteroid use was associ.....
Document: In conclusion, in patients with COVID-19, a minimum of 21 days' isolation since illness onset may be warranted even for asymptomatic patients. Old people are more likely to have serious illness with delayed clearance of viral RNA, and may require prolonged period of support and isolation. The use of antiviral drugs (chloroquine, oseltamivir, arbidol, and lopinavir/ritonavir) did not improve viral RNA clearance, while corticosteroid use was associated with delayed clearance of viral RNA and should be used with caution. All rights reserved. No reuse allowed without permission.
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