Author: Oude Munnink, Bas B; Canuti, Marta; Deijs, Martin; de Vries, Michel; Jebbink, Maarten F; Rebers, Sjoerd; Molenkamp, Richard; van Hemert, Formijn J; Chung, Kevin; Cotten, Matthew; Snijders, Fransje; Sol, Cees JA; van der Hoek, Lia
Title: Unexplained diarrhoea in HIV-1 infected individuals Document date: 2014_1_13
ID: 0e9l19kp_33
Snippet: In addition, one novel virus was identified among the VIDISCA-454 reads, which we named immunodefiencyassociated stool virus (IAS virus). The virus was present in a high concentration in stool since large numbers of sequence reads belonged to the virus (2201 of 7316 sequences, see Table 3 and Additional file 1: Table S2 ). The complete genome sequence of IAS virus was determined. This novel virus carries a dsDNA genome of 99.980 bp. The virus is .....
Document: In addition, one novel virus was identified among the VIDISCA-454 reads, which we named immunodefiencyassociated stool virus (IAS virus). The virus was present in a high concentration in stool since large numbers of sequence reads belonged to the virus (2201 of 7316 sequences, see Table 3 and Additional file 1: Table S2 ). The complete genome sequence of IAS virus was determined. This novel virus carries a dsDNA genome of 99.980 bp. The virus is exceptional because it displays no significant similarity to any of the viruses known thus far. Real time PCR confirmed that the virus is present at a high load in the sample in which the virus was discovered (1 × 10 7 DNA copies/ml).
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