Selected article for: "cleavage site and mature peptide"
Author: Wang, Shiliang; Sundaram, Jaideep P; Spiro, David
Title: VIGOR, an annotation program for small viral genomes
  • Document date: 2010_9_7
    • ID: 0lbxvudt_15
    Snippet: The rhinovirus polyprotein is cleaved into 11 mature, functional peptides by proteases. There are conserved cleavage signature sequences for 9 cleavage sites [10] . In order to predict mature peptides, the polyprotein sequence is aligned with the sequences in VIGOR's custom rhinovirus mature peptide database to identify the mature peptide cleavage sites. In the absence of a conserved signature sequence, the putative cleavage site whose products r.....
    Document: The rhinovirus polyprotein is cleaved into 11 mature, functional peptides by proteases. There are conserved cleavage signature sequences for 9 cleavage sites [10] . In order to predict mature peptides, the polyprotein sequence is aligned with the sequences in VIGOR's custom rhinovirus mature peptide database to identify the mature peptide cleavage sites. In the absence of a conserved signature sequence, the putative cleavage site whose products result in best alignments for both sequence length and similarity is selected.

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