Selected article for: "RNA virus and virus production"
Author: Natalia Fintelman-Rodrigues; Carolina Q. Sacramento; Carlyle Ribeiro Lima; Franklin Souza da Silva; André C. Ferreira; Mayara Mattos; Caroline S. de Freitas; Vinicius Cardoso Soares; Suelen da Silva Gomes Dias; Jairo R. Temerozo; Milene Miranda; Aline R. Matos; Fernando A. Bozza; Nicolas Carels; Carlos Roberto Alves; Marilda M. Siqueira; Patrícia T. Bozza; Thiago Moreno L. Souza
Title: Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production
  • Document date: 2020_4_5
    • ID: 6zk0ioep_14
    Snippet: We extended our investigation to the inhibition of SARS-CoV-2 replication by ATV using a range of different cellular systems. Vero cells are a well-known model system that produce high virus titers and display visual cytopathic effects to viral infections. ATV alone, or in combination with RTV, inhibited infectious virus production and SARS-CoV RNA levels in Vero cells ( Figure 6A and B, respectively)......
    Document: We extended our investigation to the inhibition of SARS-CoV-2 replication by ATV using a range of different cellular systems. Vero cells are a well-known model system that produce high virus titers and display visual cytopathic effects to viral infections. ATV alone, or in combination with RTV, inhibited infectious virus production and SARS-CoV RNA levels in Vero cells ( Figure 6A and B, respectively).

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