Author: Romagosa, Anna; Allerson, Matt; Gramer, Marie; Joo, Han Soo; Deen, John; Detmer, Susan; Torremorell, Montserrat
Title: Vaccination of influenza a virus decreases transmission rates in pigs Document date: 2011_12_20
ID: 0q8fedqf_60
Snippet: Although the macroscopic lung lesions in the NV group were greater than in the vaccinated groups, comparisons were only performed between treatment groups with the same endpoints. The lung lesions of the NV pigs had moderate to severe bronchoalveolar pneumonia with attenuation, hyperplasia, moderate numbers of lymphocytes admixed with macrophages in the epithelium, within the intraluminal necrotic cellular debris, and extending into the alveolar .....
Document: Although the macroscopic lung lesions in the NV group were greater than in the vaccinated groups, comparisons were only performed between treatment groups with the same endpoints. The lung lesions of the NV pigs had moderate to severe bronchoalveolar pneumonia with attenuation, hyperplasia, moderate numbers of lymphocytes admixed with macrophages in the epithelium, within the intraluminal necrotic cellular debris, and extending into the alveolar spaces. Some lung sections contained occasional bacterial colonies. The overall microscopic lesion mean score was 2.6 ± 0.48 at necropsy indicating significant interstitial pneumonia and more than 75% of the airways affected with bronchial epithelial damage.
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