Author: Romagosa, Anna; Allerson, Matt; Gramer, Marie; Joo, Han Soo; Deen, John; Detmer, Susan; Torremorell, Montserrat
Title: Vaccination of influenza a virus decreases transmission rates in pigs Document date: 2011_12_20
ID: 0q8fedqf_73
Snippet: The impact of vaccination can be assessed in this small population from results of the stochastic models by comparing the NV and HE groups. In small, naïve populations, the introduction of an influenza virus infected pig resulted in a major outbreak and infected all susceptible animals in greater than 84% of simulations. Following vaccination with a HE vaccine in a small population, the proportion of simulations in which all susceptible animals .....
Document: The impact of vaccination can be assessed in this small population from results of the stochastic models by comparing the NV and HE groups. In small, naïve populations, the introduction of an influenza virus infected pig resulted in a major outbreak and infected all susceptible animals in greater than 84% of simulations. Following vaccination with a HE vaccine in a small population, the proportion of simulations in which all susceptible animals become infected following the introduction of an infected pig was very small (< 7%). However, in the presence of HE immunity, transmission of influenza virus to susceptible animals did occur and it was not prevented in as high as 60% of the simulations as seen in HE replicate 2.
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