Selected article for: "adenovirus vaccine and recombinant adenovirus vaccine"
Author: Wang, Ting; Yin, Huiquan; Li, Yan; Zhao, Lingxiao; Sun, Xiahui; Cong, Hua
Title: Vaccination with recombinant adenovirus expressing multi-stage antigens of Toxoplasma gondii by the mucosal route induces higher systemic cellular and local mucosal immune responses than with other vaccination routes
  • Document date: 2017_4_3
    • ID: 1ay8y7li_4
    Snippet: In this research, we utilize a recombinant adenovirus vaccine expressing ubiquitin-conjugated multi-stage antigen segments (Ad-UMAS) derived from different life-cycle stages of T. gondii to evaluate the immune responses obtained with the different intramuscular vaccination routes described in our earlier study [41] . To further explore the optimal immune pathway for this recombinant adenovirus T. gondii vaccine, we plan to determine the immune re.....
    Document: In this research, we utilize a recombinant adenovirus vaccine expressing ubiquitin-conjugated multi-stage antigen segments (Ad-UMAS) derived from different life-cycle stages of T. gondii to evaluate the immune responses obtained with the different intramuscular vaccination routes described in our earlier study [41] . To further explore the optimal immune pathway for this recombinant adenovirus T. gondii vaccine, we plan to determine the immune responses and protection efficacy by vaccinating BALB/c mice via five routes (intramuscular (i.m.), intravenous (i.v.), subcutaneous (s.c.), intraoral (i.o.), and intranasal (i.n.)).

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